According to political administration of South Waziristan, a US spy plane fired two missiles at a house. Fighters of Taliban Maulvi Nazeer group were targeted in the drone.
Earlier on Wednesday, seven people were also killed in a drone strike at Datta Khel area of North Waziristan.
It should be noted that this was the first drone attack since Pakistan Army launched a military offensive in North Waziristan tribal region against the militants.