The KSE 100-share index closed down 0.35 percent or 115.93 points at 33,460.01.
Engro Foods Ltd was down to 145.18 rupees, while D.G.Khan Cement Co Ltd was down to 136.01 rupees.
The rupee ended higher at 101.55/101.65 against the dollar compared with Tuesday’s close of 101.90/101.95.
Overnight rates in the money market fell to 7.00 percent from Tuesday’s close of 7.50 percent.
